Isothiocyanate metabolism in generalist lepidopteran herbivores / vorgelegt von Katharina Schramm

Lepidopterans specialised on brassicaceous plants have been shown to possess biochemical adaptations preventing the formation of isothiocyanates. In faeces of generalist lepidopteran larvae glutathione (GSH) and cysteineglycine conjugates of plant-derived isothiocyanates were detected. The presence of GSH conjugates in larval faeces after consumption of crucifers suggests isothiocyanate-detoxification via GST (glutathione-S-transferase) activity in caterpillars. Active native GSTs were purified from midguts of Spodoptera littoralis larvae.It was shown that under conditions widely used for GST characterisation, S. littoralis-GSTs are capable of catalysing the conjugation reaction of GSH with isothiocyanates of different structures.

Saved in:
Person: Meier, Katharina [Author]
Corporate Author: Friedrich-Schiller-Universität Jena [Degree granting institution]
Format: Book
Language(s):English
Publication:Jena, 2010 [erschienen] 2011
Printing place:Jena
Dissertation:Jena, Univ., Diss., 2011
Subjects:Herbivoren > Pflanzeninhaltsstoff > Entgiftung
Type of content:Hochschulschrift
Related resources:Erscheint auch als Online-Ausgabe: Isothiocyanate metabolism in generalist lepidopteran herbivores
Physical description:II, 114 S. : Ill., graph. Darst. ; 29,5 cm
Basic Classification: 42.75 Insecta
42.63 Tierphysiologie